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Granzyme B knockdown suppresses cell proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive synovial inflammation, cartilage and bone destruction. Although granzyme B (GZMB) can prevent osteocartilaginous destruction and promote bone formation, its effects and molecular mechanisms in RA remain...

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Bibliografske podrobnosti
Principais autores: Wei Zhang, Weike Tian, Chao Zhang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-06-01
Serija:Frontiers in Cell and Developmental Biology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fcell.2026.1679672/full
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