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Treponema pallidum TprD and TprK are adhesins and their surface expression promotes spirochetal opsonophagocytosis

BackgroundTreponema pallidum subspecies pallidum causes systemic syphilis, exclusively infects humans in nature and can persist for decades in the absence of treatment despite generating robust adaptive immune responses. The T. pallidum repeat (Tpr) family of outer membrane proteins are immunogenic...

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Hauptverfasser: Kashaf Zafar, Onyedikachi C. Azuama, Linda H. Xu, Lorenzo Giacani, Nikhat Parveen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-03-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1783902/full
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