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Spatiotemporal analysis of induced neural stem cell therapy to overcome advanced glioblastoma recurrence

Genetically engineered neural stem cells (NSCs) are a promising therapy for the highly aggressive brain cancer glioblastoma (GBM); however, treatment durability remains a major challenge. We sought to define the events that contribute to dynamic adaptation of GBM during treatment with human skin-der...

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Autors principals: Andrew B. Satterlee, Denise E. Dunn, Alain Valdivia, Daniel Malawsky, Andrew Buckley, Timothy Gershon, Scott Floyd, Shawn Hingtgen
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2022-09-01
Col·lecció:Molecular Therapy: Oncolytics
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2372770522000821
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