Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

<p>Abstract</p> <p>Background</p> <p>The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1) is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4⁺ T lymphocytes. Tax permanently stimulates this pathway at a cytoplasmic l...

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Detalhes bibliográficos

Principais autores:	Bonnet Amandine, Randrianarison-Huetz Voahangy, Nzounza Patrycja, Nedelec Martine, Chazal Maxime, Waast Laetitia, Pene Sabrina, Bazarbachi Ali, Mahieux Renaud, Bénit Laurence, Pique Claudine
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-09-01
coleção:	Retrovirology
Assuntos:	Retrovirus Leukemia NF-kappaB Ubiquitin SUMO Nuclear speckles
Acesso em linha:	http://www.retrovirology.com/content/9/1/77
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