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The Synthesis of 2,5-Dioxaspiro[3.4]octane Building Blocks: Three-Dimensional Spirocyclic Analogs of 1,4-Dioxanes

A ring-closing metathesis (RCM) strategy was employed for the synthesis of spirooxetane compounds with a tetrahydrofuran (THF) core. The approach proposed relied on the preparation of an unsaturated spirooxetane from vinyl oxetanol. The reaction sequence involved the NaH-mediated О-alkylation with m...

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Bibliografische Detailangaben
Hauptverfasser: Bohdan V. Vashchenko, Eduard V. Litskan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National University of Pharmacy (Kharkiv) 2025-04-01
Schriftenreihe:Журнал органічної та фармацевтичної хімії
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Online-Zugang:https://ophcj.nuph.edu.ua/article/view/324901
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