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The fT3/fT4 ratio as a candidate marker of motor progression in SCA3

Background: Motor severity and progression in spinocerebellar ataxia type 3 (SCA3) vary across individuals, yet physiological factors contributing to this heterogeneity remain incompletely understood. Thyroid hormones are central regulators of systemic metabolism and are associated with motor functi...

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Principais autores: Mengyuan Dong, Ziyan Ding, Zhao Chen, Na Wan, Linliu Peng, Qinlin Huang, Jian Hu, Ziting Cui, Rongfan Peng, Daren Zeng, Ying Zou, Yiqing Gong, Yan Tan, Daji Chen, Qian Jiang, Jiawei He, Zhuan Pei, Siyu Ding, Xiaokai Shen, Qi Wu, Qi Deng, Hongyu Yuan, Chunrong Wang, Linlin Wan, Lang He, Huirong Peng, Yuting Shi, Rong Qiu, Hong Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-09-01
coleção:Neurobiology of Disease
Assuntos:
Spinocerebellar ataxia type 3
Cerebellum
Hypothalamic-pituitary-thyroid axis
Motor progression
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996126002196
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