Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge

Abstract Vaccines based on live attenuated Chlamydia elementary bodies (EBs) can cause disease in vaccinated animals and the comparably safer inactivated whole EBs are only marginally protective. Recent studies show that a vaccine formulation comprising UV-inactivated EBs (EB) and appropriate mucosa...

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Detalhes bibliográficos

Principais autores:	Zonghui Zuo, Yongjuan Zou, Qiang Li, Yongxia Guo, Tianyuan Zhang, Jie Wu, Cheng He, Francis O. Eko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-05-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-89940-8
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