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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma

Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade glioma, and confers a poor prognosis. While therapeutic histone deacetylase (HDAC) inhibition of diffuse intrinsic pontine glioma (DIPG) has been...

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Kaydedildi:
Asıl Yazarlar: Alyssa Noll, Carrie Myers, Matthew C. Biery, Michael Meechan, Sophie Tahiri, Asmitha Rajendran, Michael E. Berens, Danyelle Paine, Sara Byron, Jiaming Zhang, Conrad Winter, Fiona Pakiam, Sarah E.S. Leary, Bonnie L. Cole, Evangeline R. Jackson, Matthew D. Dun, Jessica B. Foster, Myron K. Evans, Siobhan S. Pattwell, James M. Olson, Nicholas A. Vitanza
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2023-09-01
Seri Bilgileri:Neoplasia: An International Journal for Oncology Research
Konular:
Diffuse intrinsic pontine glioma (DIPG)
Hypermutant
Mismatch-repair (MMR)
Histone deacetylase inhibitor (HDACi)
Quisinostat
Online Erişim:http://www.sciencedirect.com/science/article/pii/S1476558623000465
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