Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway

Abstract Background Cisplatin (DDP) is one of the most effective anticancer drugs, commonly used to treat advanced ovarian cancer (OC). However, DDP has significant limitations of platinum-based drugs, including chemical resistance and high-dose toxic side effects. Traditional Chinese medicines (TCM...

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Autori principali:	Xue Sui, Bingqing Gao, Liu Zhang, Yanmin Wang, Junnan Ma, Xingchen Wu, Chenyu Zhou, Min Liu, Lin Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-12-01
Serie:	Journal of Ovarian Research
Soggetti:	Scutellaria barbata D.Don and Hedyotis diffusa Willd Ovarian cancer DDP chemosensitivity NRF2/HO-1 Oxidative stress Ferritin autophagic degradation
Accesso online:	https://doi.org/10.1186/s13048-024-01570-6
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