Hierarchical PLGA/PEG Barrier Engineering of Alginate Hydrogels: Scale-Dependent Burst-Release Control in Beads and Microgels

Alginate hydrogels offer mild ionic gelation and tunable porosity for drug delivery, yet their hydrophilic, macroporous networks suffer from rapid initial burst release of water-soluble payloads. Here we introduce a hierarchical barrier-engineering strategy in which poly(D,L-lactide-co-glycolide)/po...

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Autori principali:	Junseok Lee, Heeyoung Lee, Myeongjun Kim, Dae Gyu Song, Jaewon Jang, Jeong Koo Kim, Hong Jin Choi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-05-01
Serie:	Biomimetics
Soggetti:	alginate hydrogel PLGA/PEG coating burst release core–shell dip-coating scale-dependent release
Accesso online:	https://www.mdpi.com/2313-7673/11/5/353
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