Randomised, open-label, multicentric phase III trial to evaluate the safety and efficacy of palbociclib in combination with endocrine therapy, guided by ESR1 mutation monitoring in oestrogen receptor-positive, HER2-negative metastatic breast cancer patients: study design of PADA-1
Introduction The combination of a CDK4/6 inhibitor with an aromatase inhibitor (AI) has recently become the gold standard for AI-sensitive first line treatment of oestrogen receptor-positive (ER+) HER2-negative (HER2−) advanced breast cancer. However, most patients receiving this combination will ul...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BMJ Publishing Group
2022-03-01
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| Saila: | BMJ Open |
| Sarrera elektronikoa: | https://bmjopen.bmj.com/content/12/3/e055821.full |
| Etiketak: |
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