A novel, non-canonical splice variant of the Ikaros gene is aberrantly expressed in B-cell lymphoproliferative disorders.

The Ikaros gene encodes a Krüppel-like zinc-finger transcription factor involved in hematopoiesis regulation. Ikaros has been established as one of the most clinically relevant tumor suppressors in several hematological malignancies. In fact, expression of dominant negative Ikaros isoforms is associ...

Полное описание

Библиографические подробности

Главные авторы:	Daria Capece, Francesca Zazzeroni, Maria Michela Mancarelli, Daniela Verzella, Mariafausta Fischietti, Ambra Di Tommaso, Rita Maccarone, Sara Plebani, Mauro Di Ianni, Alberto Gulino, Edoardo Alesse
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2013-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC3706598?pdf=render
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