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Staphylococcal enterotoxin C2 rescued simulated microgravity-induced bone loss and the trans-differentiation of BMSCs into adipocytes

Abstract Exposure to microgravity decreases bone volume and increases marrow fat, partly due to impaired BMSC osteogenesis and enhanced adipogenesis. Staphylococcal enterotoxin C2 (SEC2) can influence BMSC differentiation, potentially promoting osteogenesis. This study investigated SEC2’s effects on...

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Principais autores: Nan Hou, Zhengmeng Yang, Haixing Wang, Xuan Lu, Shanshan Bai, Yaofeng Wang, Sien Lin, Micky D. Tortorella, Lu Feng, Gang Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-12-01
Serier:npj Microgravity
Online adgang:https://doi.org/10.1038/s41526-025-00548-y
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