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An increased fraction of circulating miR-363 and miR-16 is particle bound in patients with chronic lymphocytic leukaemia as compared to normal subjects

Abstract Objectives In vitro culture studies have shown that miR-363 is enriched in extracellular vesicles from chronic lymphocytic leukaemia cells. We wondered whether miR-363 was detectable in plasma, which is an essential precondition for further studies to assess its usefulness as a biomarker. U...

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Principais autores: Afaf Alharthi, Daniel Beck, Dena R. Howard, Peter Hillmen, Melanie Oates, Andrew Pettitt, Simon D. Wagner
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-05-01
Series:BMC Research Notes
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Acceso en liña:http://link.springer.com/article/10.1186/s13104-018-3391-9
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