Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

Abstract Background Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in malignancy, invasion and chemoresistance between cancer types and subt...

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Autors principals:	Julie A. MacDonald, Niharika Kura, Carleigh Sussman, Dori C. Woods
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-10-01
Col·lecció:	Journal of Ovarian Research
Matèries:	Granulosa cell tumor KGN Mitochondria Metabolism TRAIL BIRC5
Accés en línia:	http://link.springer.com/article/10.1186/s13048-018-0463-3
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