Colchicine as inhibitor of caspase-1 and GSTO-1 to regulate inflammation-induced pyroptosis in ischemic heart disease: A computational investigation

Context: Inflammation-induced pyroptosis amplification contributes to the deterioration of ischemic heart diseases (IHD). Triggered by inflammasome activation, it provokes inflammatory reactions involving proteins such as glutathione transferase omega-1 (GSTO-1), NLRP-3 inflammasome, and caspase-1 (...

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Detalhes bibliográficos

Principais autores:	Budi Satrijo, Mohammad S. Rohman, Aswoco A. Asmoro, Hani Susianti, Diana Lyrawati, Rislan F. Muhammad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	GarVal Editorial Ltda. 2025-05-01
coleção:	Journal of Pharmacy & Pharmacognosy Research
Assuntos:	caspase-1 inhibitor colchicine glutathione transferase omega-1 inhibitor ischemic heart disease pyroptosis
Acesso em linha:	https://jppres.com/jppres/pdf/vol13/jppres24.2034_13.3.744.pdf
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