Prospero-related homeobox protein 1 (Prox1) enhances myelin sheath regeneration in injured sciatic nerve

Background: Peripheral nerve injury (PNI), such as sciatic nerve injury (SNI), often results in poor functional recovery due to myelin damage, which critically impairs nerve regeneration. Prox1, a homeobox transcription factor known to influence neurogenesis, has not been studied in peripheral myeli...

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Autori principali:	Linlin Jie, Xuening Jing, Jie Liu, Jun Ren, Xiaoni Kong, Jun Wu, Fanwei Meng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-12-01
Serie:	IBRO Neuroscience Reports
Soggetti:	Sciatic nerve injury Myelin sheath injury Myelin sheath regeneration Prox1 MBP Schwann Cells
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2667242125001526
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