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Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome

Background: Diabetic nephropathy (DN) is one of the leading causes of chronic kidney disease (CKD) worldwide, tubular injury is the driving force during the pathogenesis and progression of DN. Thus, we aim to utilize the connectivity map (CMap) with renal tubulointerstitial transcriptomic profiles o...

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Auteurs principaux: Qing Hou, Shuyan Kan, Zhuang Wang, Jinsong Shi, Caihong Zeng, Dahai Yang, Song Jiang, Zhihong Liu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-07-01
Collection:Frontiers in Pharmacology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fphar.2022.938391/full
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