Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Abstract Preclinical rodent models suggest that psychosis involves alterations in the activity and glutamatergic function in the hippocampus, driving dopamine activity through projections to the striatum. The extent to which this model applies to the onset of psychosis in clinical subjects is unclea...

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Principais autores:	Paul Allen, Emily J. Hird, Natasza Orlov, Gemma Modinos, Matthijs Bossong, Mathilde Antoniades, Carly Sampson, Matilda Azis, Oliver Howes, James Stone, Jesus Perez, Matthew Broome, Antony A. Grace, Philip McGuire
格式:	Artigo
語言:	Inglês
出版:	Nature Publishing Group 2021-11-01
叢編:	Translational Psychiatry
在線閱讀:	https://doi.org/10.1038/s41398-021-01705-z
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