Identification of stigmasterol derived AChE inhibitors for Alzheimer’s disease using high throughput virtual screening and molecular dynamics simulations

Abstract Alzheimer’s disease (AD), a progressive neurodegenerative disorder, poses a significant global health burden due to its intricate pathology and the absence of curative treatments. Current therapies primarily offer symptomatic relief, often with limited efficacy and complications, thereby un...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	M. Oliur Rahman, Sheikh Sunzid Ahmed, Ali S. Alqahtani, Md Tabish Rehman, Nahid Sultana, Mohamed Bouhrim, Mohammad Ajmal Ali, Joongku Lee
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2025-10-01
Sarja:	Scientific Reports
Aiheet:	Stigmasterol Alzheimer’s MD simulation MM/GBSA HTVS DFT
Linkit:	https://doi.org/10.1038/s41598-025-20527-3
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