Genetic polymorphism and evidence of signatures of selection in the Plasmodium falciparum circumsporozoite protein gene in Tanzanian regions with different malaria endemicity

Abstract Background In 2021 and 2023, the World Health Organization approved RTS,S/AS01 and R21/Matrix M malaria vaccines, respectively, for routine immunization of children in African countries with moderate to high transmission. These vaccines are made of Plasmodium falciparum circumsporozoite pro...

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Principais autores:	Beatus M. Lyimo, Catherine Bakari, Zachary R. Popkin-Hall, David J. Giesbrecht, Misago D. Seth, Dativa Pereus, Zulfa I. Shabani, Ramadhan Moshi, Ruth Boniface, Celine I. Mandara, Rashid Madebe, Jonathan J. Juliano, Jeffrey A. Bailey, Deus S. Ishengoma
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-05-01
סדרה:	Malaria Journal
נושאים:	Plasmodium falciparum Circumsporozoite protein Malaria vaccine Genetic diversity Signature of selection Tanzania
גישה מקוונת:	https://doi.org/10.1186/s12936-024-04974-3
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!