Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease

Abstract Alzheimer’s disease (AD), characterized by the deposition of amyloid-β (Aβ) in senile plaques and neurofibrillary tangles of phosphorylated tau (pTau), is increasingly recognized as a complex disease with multiple pathologies. AD sometimes pathologically overlaps with age-related tauopathie...

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Autors principals:	Ana-Caroline Raulin, Sydney V. Doss, Michael G. Heckman, Emily C. Craver, Zonghua Li, Tadafumi C. Ikezu, Hiroaki Sekiya, Chia-Chen Liu, Yuka A. Martens, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Michael DeTure, R. Ross Reichard, Aivi T. Nguyen, Eleni Constantopoulos, Rachel A. Larsen, Emmaline K. Kounaves, Melissa E. Murray, Dennis W. Dickson, Ronald C. Petersen, Guojun Bu, Takahisa Kanekiyo
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-02-01
Col·lecció:	Acta Neuropathologica Communications
Matèries:	Amyloid-β Alzheimer’s disease Apolipoprotein E Argyrophilic grain disease MMSE Tau
Accés en línia:	https://doi.org/10.1186/s40478-024-01731-0
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