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Investigation of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions and performance of a rapid diagnostic test for identifying asymptomatic malaria infection in northern Ethiopia, 2015

Abstract Background Rapid diagnostic tests (RDTs) are widely used for malaria diagnosis of both symptomatic and asymptomatic infections. Although RDTs are a reliable and practical diagnostic tool, the sensitivity of histidine-rich protein 2 (HRP2)-based RDTs can be reduced if pfhrp2 or pfhrp3 (pfhrp...

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Detalhes bibliográficos
Principais autores: Colleen M. Leonard, Ashenafi Assefa, Jessica N. McCaffery, Camelia Herman, Mateusz Plucinski, Heven Sime, Hussein Mohammed, Amha Kebede, Hiwot Solomon, Mebrahtom Haile, Matt Murphy, Jimee Hwang, Eric Rogier
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-03-01
coleção:Malaria Journal
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Acesso em linha:https://doi.org/10.1186/s12936-022-04097-7
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