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Metabolic engineering of Streptomyces roseosporus for increased production of clinically important antibiotic daptomycin

Abstract Daptomycin (DAP), a novel cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, is clinically important for treatment of infections caused by multidrug‐resistant Gram‐positive pathogens, but the low yield hampers its large‐scale industrial production. Here, we describe a combi...

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Váldodahkkit: Xingwang Li, Ziwei Sang, Xuejin Zhao, Ying Wen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2024-11-01
Ráidu:Microbial Biotechnology
Liŋkkat:https://doi.org/10.1111/1751-7915.70038
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