Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin.

<h4>Background</h4>The innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells. One such pattern-recognition molecule is M-ficolin, which is capable of activating the complement system thro...

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Bibliografiske detaljer

Principais autores:	Christian Gytz Ammitzbøll, Troels Rønn Kjær, Rudi Steffensen, Kristian Stengaard-Pedersen, Hans Jørgen Nielsen, Steffen Thiel, Martin Bøgsted, Jens Christian Jensenius
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2012-01-01
Serier:	PLoS ONE
Online adgang:	https://doi.org/10.1371/journal.pone.0050585
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