Cuproptosis and its potential role in musculoskeletal disease

Cuproptosis, a recently identified form of copper-dependent cell death, arises from intracellular copper dyshomeostasis. As an essential trace element, copper plays a critical role in bioenergetic metabolism, redox regulation, and synaptic transmission. However, excessive copper exerts cytotoxic eff...

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Autors principals:	Ziyang Xiang, Huiling Mei, Honglin Wang, Xiaoyue Yao, Ji Rao, Wentao Zhang, Aoshuang Xu, Lin Lu
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-04-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	cuproptosis osteoporosis osteoarthritis osteosarcoma intervertebral disc degeneration spinal cord injury
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1570131/full
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