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The role of ABCB1 and CES1 genotypes on the efficacy and safety of dabigatran: a systematic review and meta-analysis

Abstract Introduction : Dabigatran is a direct oral anticoagulant associated with a high incidence of gastrointestinal bleeding, which presents a significant clinical concern. Genetic polymorphisms in the enzymes responsible for drug absorption (ABCB1) and activation (CES1) may influence dabigatran’...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Weam Aldiban, Nada G. Hamam, Nereen A. Almosilhy, Kholoud Elsamman, Mohamed Wagdy, Doaa Mashaly, Suhel F. Batarseh, Youssef El-Sherif, Basma Badrawy Khalefa, Zina Otmani
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-10-01
Rangatū:Human Genomics
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s40246-025-00836-4
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