Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques. Sufficient clearance of myelin and cellular debris is one of the requirements for proper tissue repair and remyelination. The mechanisms underly...

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Váldodahkkit:	Alwin Kamermans, Merel Rijnsburger, Ananya Chakraborty, Susanne van der Pol, Helga E. de Vries, Jack van Horssen
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2019-05-01
Ráidu:	Frontiers in Immunology
Fáttát:	angiopoietin-like 4 multiple sclerosis phagocytes astrocyte lipoprotein-lipase remyelination
Liŋkkat:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00950/full
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