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Protective Effects of Trimetazidine and Dexmedetomidine on Liver Injury in a Mesenteric Artery Ischemia–Reperfusion Rat Model via Endoplasmic Reticulum Stress

Background/Objectives: Acute mesenteric ischemia can lead to severe liver damage due to ischemia–reperfusion (I/R) injury. This study investigated the protective effects of trimetazidine (TMZ) and dexmedetomidine (DEX) against liver damage induced by mesenteric artery I/R via endoplasmic reticulum s...

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Principais autores: Sedat Ciftel, Tolga Mercantepe, Riza Aktepe, Esra Pinarbas, Zulkar Ozden, Adnan Yilmaz, Filiz Mercantepe
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-10-01
Serier:Biomedicines
Fag:
dexmedetomidine
trimetazidine
endoplasmic reticulum stress
liver
mesenteric artery ischemia
ischemia–reperfusion injury
Online adgang:https://www.mdpi.com/2227-9059/12/10/2299
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