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NOTCH and Graft-Versus-Host Disease

In allogeneic hematopoietic stem cell transplantation, which is the major curative therapy for hematological malignancies, T cells play a key role in the development of graft-versus-host disease (GvHD). NOTCH pathway is a conserved signal transduction system that regulates T cell development and dif...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Mauro Di Ianni, Beatrice Del Papa, Stefano Baldoni, Ambra Di Tommaso, Bianca Fabi, Emanuela Rosati, Annalisa Natale, Stella Santarone, Paola Olioso, Gabriele Papalinetti, Raffaella Giancola, Patrizia Accorsi, Paolo Di Bartolomeo, Paolo Sportoletti, Franca Falzetti
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2018-08-01
Rangatū:Frontiers in Immunology
Ngā marau:
NOTCH
graft-versus-host disease
tolerance
graft-versus-leukemia
HSCT
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fimmu.2018.01825/full
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