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Genomic instability in human actinic keratosis and squamous cell carcinoma

OBJECTIVE: To compare the repetitive DNA patterns of human actinic keratoses and squamous cell carcinomas to determine the genetic alterations that are associated with malignant transformation. INTRODUCTION: Cancer cells are prone to genomic instability, which is often due to DNA polymerase slippage...

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Principais autores: Luciana Sanches Cabral, Cyro Festa Neto, José A. Sanches Jr, Itamar R. G. Ruiz
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier España 2011-01-01
Serier:Clinics
Fag:
Squamous cell carcinoma
Actinic keratosis
Microsatellite instability
RAPD
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400001
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