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Active removal of inhibitory components drives the flagellar type 3 secretion-specificity switch

ABSTRACT Type 3 secretion (T3S) systems assemble bacterial nanomachines, including the flagellum and virulence-associated injectisomes, by exporting distinct classes of substrates in a defined temporal order. In both systems, completion of an early assembly intermediate triggers an irreversible swit...

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Principais autores: Fabienne F. V. Chevance, Dara Niketic, DingBang Wu, Carl Ty Mellor, David F. Blair, Sherwood R. Casjens, Miki Kinoshita, Keiichi Namba, Tohru Minamino, Kelly T. Hughes
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2026-07-01
Serier:mBio
Fag:
flagella
secretion
nanomachine
type III secretion
secretion-specificity switch
Online adgang:https://journals.asm.org/doi/10.1128/mbio.01037-26
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