The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling in Caenorhabditis elegans

Gq is a heterotrimeric G protein that is widely expressed in neurons and regulates neuronal activity. To identify pathways regulating neuronal Gq signaling, we performed a forward genetic screen in Caenorhabditis elegans for suppressors of activated Gq. One of the suppressors is an allele of sek-1,...

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Principais autores:	Jill M. Hoyt, Samuel K. Wilson, Madhuri Kasa, Jeremy S. Rise, Irini Topalidou, Michael Ailion
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2017-09-01
Serija:	G3: Genes, Genomes, Genetics
Teme:	p38 MAPK pathway Gq signaling animal behavior C. elegans
Online dostop:	http://g3journal.org/lookup/doi/10.1534/g3.117.043273
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