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FleQ finetunes the expression of a subset of BrlR-activated genes to enable antibiotic tolerance by Pseudomonas aeruginosa biofilms

ABSTRACT The transcriptional regulator FleQ contributes to Pseudomonas aeruginosa biofilm formation by activating the expression and biosynthesis of matrix exopolysaccharides in a manner dependent on c-di-GMP. However, little is known about the role of FleQ in the antibiotic tolerance phenotype of P...

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Autors principals: Victoria I. Oladosu, Karin Sauer
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2025-05-01
Col·lecció:Journal of Bacteriology
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Accés en línia:https://journals.asm.org/doi/10.1128/jb.00503-24
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