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Transcriptomic Analysis Reveals the Beneficial Effects of Spermidine in an ALS Mouse Model

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease marked by progressive degeneration of motor neurons and skeletal muscle. Gene expression analysis of the spinal cord and gastrocnemius of the SOD1-G93A ALS mouse model revealed a strong increase in inflammatory pathways and, sp...

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Principais autores: Cristian Fiorucci, Marianna Nicoletta Rossi, Rachele Di Santo, Illari Salvatori, Silvia Scaricamazza, Stefano Giuliani, Olga Carletta, Ermes Filomena, Davide Laurenti, Roberto Mattioli, Luciana Mosca, Cristiana Valle, Alberto Ferri, Anna Maria D'Erchia, Manuela Cervelli
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-04-01
Serier:Biomolecules
Fag:
amyotrophic lateral sclerosis
spermidine
polyamines
Online adgang:https://www.mdpi.com/2218-273X/16/4/566
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