Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA–BamD Interaction

The demand for novel antibiotics is imperative for drug-resistant Gram-negative bacteria which causes diverse intractable infection disease in clinic. Here, a comprehensive screening was implemented to identify potential agents that disrupt the assembly of β-barrel outer-membrane proteins (OMPs) in...

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Bibliografische Detailangaben

Hauptverfasser:	Yan Li, Xiaohong Zhu, Jing Zhang, Yuan Lin, Xuefu You, Minghua Chen, Yanchang Wang, Ningyu Zhu, Shuyi Si
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2020-06-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	outer-membrane proteins Escherichia coli BamA–BamD yeast two-hybrid antibacterial agent
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01252/full
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