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Exploring the common ferroptosis-related genes and molecular mechanisms in periodontitis and systemic sclerosis via integrated bioinformatics and experimental analysis

BackgroundAccumulating evidence suggests reciprocal risk factors between periodontitis (PD) and systemic sclerosis (SSc). Ferroptosis, an iron-dependent and immune-related form of cell death, has been implicated in both diseases, yet its shared molecular mechanisms remain largely unclear.MethodsBidi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Shengchao Zhang, Shengwei Yang, Cui Ge, Chao Ji, Ruohan Lin, Wenjuan Xue, Dongxiu Liu, Fulin Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-04-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
Schlagworte:
bioinformatics
ferroptosis
machine learning
periodontitis
systemic sclerosis
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2026.1803091/full
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