Optimization of lentiviral delivery of barcoded anti-CD20 chimeric antigen receptors into rhesus macaque and human natural killer cells

Natural killer (NK) cells are pivotal in immunosurveillance and hold great potential for immunotherapy due to their ability to target malignant cells. Their low risk of causing graft-versus-host disease (GvHD) post-allogenic transplantation underscores their potential as an off-the shelf cellular th...

Descripción completa

Detalles Bibliográficos

Autores principales:	Taha B. Hayal, Aman A. Mulla, David S.J. Allan, Brynn B. Duncan, Saanika Joshi, So Gun Hong, Rafet Basar, Katayoun Rezvani, Richard W. Childs, Chuanfeng Wu, Cynthia E. Dunbar
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-06-01
Colección:	Molecular Therapy: Methods & Clinical Development
Materias:	natural killer cell, NK cell Poloxamer 407 lentiviral transduction CAR-NK IL-15 barcode clonal tracking
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2329050125000683
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!