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Separase Inhibition Enhances Gefitinib Sensitivity of Lung Cancer via PTBP1/TAK1/RIPK1‐Mediated PANoptosis

ABSTRACT Gefitinib is the most frequently employed anti‐lung cancer drug, but its clinical effectiveness is often compromised due to the development of drug resistance. Given that gefitinib failure to long‐term inhibition of the growth of lung carcinoma cell lines, which mirrors the resistance obser...

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Principais autores: Zhouyangfan Peng, Liangpeng Xie, Sufang Zhou, Yapei Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-11-01
Serier:MedComm
Fag:
gefitinib
lung cancer
PANoptosis
RIPK1
separase
TAK1
Online adgang:https://doi.org/10.1002/mco2.70432
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