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Structure, Polymorphisms and Electrochemistry of Mammalian Metallothioneins – A Review

Mammalian metallothioneins (MTs) are cysteine-rich low-molecular mass proteins with numerous functions including toxic metal detoxification, as a metal chaperone and maintenance of metal ion homeostasis. Four major isoforms (MT-1 through MT-4) have been identified in mammals. In this review, the fun...

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Main Authors: Helena Skutkova, Petr Babula, Marie Stiborova, Tomas Eckschlager, Libuse Trnkova, Ivo Provaznik, Jaromir Hubalek, Rene Kizek, Vojtech Adam
Format: Artigo
Language:Inglês
Published: Elsevier 2012-12-01
Series:International Journal of Electrochemical Science
Subjects:
Metallothionein
Isoforms
Bioinformatics
Data Analysis
Phylogeny
DNA Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S1452398123165552
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