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Characterisation of the immune repertoire of a humanised transgenic mouse through immunophenotyping and high-throughput sequencing

Immunoglobulin loci-transgenic animals are widely used in antibody discovery and increasingly in vaccine response modelling. In this study, we phenotypically characterised B-cell populations from the Intelliselect Transgenic mouse (Kymouse) demonstrating full B-cell development competence. Compariso...

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書誌詳細
主要な著者: Eve Richardson, Špela Binter, Miha Kosmac, Marie Ghraichy, Valentin von Niederhäusern, Aleksandr Kovaltsuk, Jacob D Galson, Johannes Trück, Dominic F Kelly, Charlotte M Deane, Paul Kellam, Simon J Watson
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications Ltd 2023-03-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/81629
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