Significance of interferon signaling based on mRNA-microRNA integration and plasma protein analyses in critically ill COVID-19 patients

We evaluated mRNA and miRNA in COVID-19 patients and elucidated the pathogenesis of COVID-19, including protein profiles, following mRNA and miRNA integration analysis. mRNA and miRNA sequencing was done on admission with whole blood of 5 and 16 healthy controls (HCs) and 10 and 31 critically ill CO...

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Bibliografske podrobnosti

Principais autores:	Yuki Togami, Hisatake Matsumoto, Jumpei Yoshimura, Tsunehiro Matsubara, Takeshi Ebihara, Hiroshi Matsuura, Yumi Mitsuyama, Takashi Kojima, Masakazu Ishikawa, Fuminori Sugihara, Haruhiko Hirata, Daisuke Okuzaki, Hiroshi Ogura
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2022-09-01
Serija:	Molecular Therapy: Nucleic Acids
Teme:	MT: Non-coding RNAs IFN-β IFN-λ1 IL-27 type I IFN type III IFN
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2162253122001743
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