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Ameliorative effects of combination therapy with metformin and crocin in experimental colitis in rats

Background and purpose: Inflammatory bowel disease (IBD) is characterized by aberrant immune responses in the colon, leading to the inflammatory cascades. Metformin (MTF) and crocin demonstrated beneficial effects in reducing inflammation and oxidative stress, as the main triggers of IBD. Considerin...

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Principais autores: Bahare Koohshekan, Mohsen Minaiyan, Mohammad Hashemnia, Mohammad Hosein Aarabi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2025-11-01
coleção:Research in Pharmaceutical Sciences
Assuntos:
crocin
inflammation
inflammatory bowel disease
metformin
rat
ulcerative colitis
Acesso em linha:https://journals.lww.com/10.4103/RPS.RPS_121_24
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