Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK–LCN2 pathway

Abstract Background Sepsis-associated acute kidney injury (SA-AKI), one of the most common complications of sepsis, significantly prolongs hospitalization, increases mortality, and elevates risks of cardiovascular events and chronic kidney disease. Critically, there are insufficient effective and sa...

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Autori principali:	Boyang Liu, Shengxiang Ao, Li Luo, Lin Qiao, Tianyin Kuang, Hongyan Xiao, Jing Zhou, Shuangqin Yin, Huaping Liang, Fen Li, Weihong Dai, Junyu Zhu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-01-01
Serie:	European Journal of Medical Research
Soggetti:	Dexmedetomidine Sepsis-associated acute kidney injury Ferroptosis LCN2
Accesso online:	https://doi.org/10.1186/s40001-026-03953-5
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