Moving beyond the mousetrap: current and emerging humanized mouse and rat models for investigating prevention and cure strategies against HIV infection and associated pathologies

Abstract The development of safe and effective combination antiretroviral therapies for human immunodeficiency virus (HIV) infection over the past several decades has significantly reduced HIV-associated morbidity and mortality. Additionally, antiretroviral drugs have provided an effective means of...

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Hlavní autoři:	Yash Agarwal, Cole Beatty, Shivkumar Biradar, Isabella Castronova, Sara Ho, Kevin Melody, Moses Turkle Bility
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-04-01
Edice:	Retrovirology
Témata:	Humanized mouse and rat models Modeling HIV infection and reservoir Modeling human anti-HIV immune response In vivo models for HIV cure Animal models for HIV vaccines
On-line přístup:	http://link.springer.com/article/10.1186/s12977-020-00515-3
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