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Efficacy and safety of neoadjuvant chemotherapy with immunotherapy versus chemotherapy alone in esophageal squamous cell carcinoma: a meta-analysis based on randomized controlled trials

BackgroundEsophageal squamous cell carcinoma (ESCC) remains one of the most aggressive and lethal cancers, with high incidence and mortality rates in East Asia. Neoadjuvant chemotherapy (NC) has traditionally been the standard approach for improving resectability in ESCC, but its limited efficacy in...

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Principais autores: Yibang Ye, Liangyu Zhang, Zhenyuan Yang, Yizhou Huang, Maohui Chen, Shuliang Zhang, Taidui Zeng, Chun Chen, Bin Zheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
esophageal squamous cell carcinoma
immune checkpoint inhibitors
meta-analysis
neoadjuvant chemoimmunotherapy
neoadjuvant chemotherapy
randomized controlled trials
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1825905/full
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