Localized delivery of therapeutic doxorubicin dose across the canine blood–brain barrier with hyperthermia and temperature sensitive liposomes

Most drugs cannot penetrate the blood–brain barrier (BBB), greatly limiting the use of anti-cancer agents for brain cancer therapy. Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug in response to hyperthermia (>40 °C). Since hyperthermia also transientl...

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Principais autores:	Amy Lee Bredlau, Anjan Motamarry, Chao Chen, M. A. McCrackin, Kris Helke, Kent E. Armeson, Katrina Bynum, Ann-Marie Broome, Dieter Haemmerich
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis Group 2018-01-01
Series:	Drug Delivery
Assuntos:	thermosensitive liposomes thermal therapy blood–brain barrier hyperthermia doxorubicin liposomes
Acceso en liña:	http://dx.doi.org/10.1080/10717544.2018.1461280
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