Orthogonal in vivo and in vitro membrane engineering enables human-like lipid remodeling of bacterial magnetosomes for functional TrkA display

ABSTRACT The magnetotactic bacterium Magnetospirillum magneticum produces biogenic magnetic nanoparticles called magnetosomes, each comprising a magnetite core surrounded by a lipid bilayer. By expressing the human neurotrophin receptor TrkA, which is implicated in Alzheimer’s disease, cancer, and o...

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Bibliografische Detailangaben

Hauptverfasser:	Ryoto Tomoe, Shunya Waki, Keita Morimoto, Takaho Ogaki, Tsuyoshi Tanaka, Tomoko Yoshino
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2025-12-01
Schriftenreihe:	Applied and Environmental Microbiology
Schlagworte:	tropomyosin receptor kinase A magnetosome magnetotactic bacterium cholesterol lipid membrane
Online-Zugang:	https://journals.asm.org/doi/10.1128/aem.01710-25
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