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Mpox virus Clade IIb infected Cynomolgus macaques via mimic natural infection routes closely resembled human mpox infection

ABSTRACTGenerating an infectious non-human primate (NHP) model using a prevalent monkeypox virus (MPXV) strain has emerged as a crucial strategy for assessing the efficacy of vaccines and antiviral drugs against human MPXV infection. Here, we established an animal model by infecting cynomolgus macaq...

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Principais autores: Qingni Li, Yunfeng Chen, Wenjing Zhang, Chunyang Li, Ding Tang, Wanlu Hua, Fan Hou, Zhuo Chen, Yuanlang Liu, Yi Tian, Kaili Sun, Xiuli Xu, Yan Zeng, Fei Xia, Jia Lu, Zejun Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Emerging Microbes and Infections
Assuntos:
MPXV
Clade IIb
Cynomolgus macaques
multiple routes
typical symptoms
Acesso em linha:https://www.tandfonline.com/doi/10.1080/22221751.2024.2332669
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