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First-line treatment of EGFR-mutated non-small cell lung cancer with brain metastases: a systematic review and meta-analysis

Abstract This systematic review and network meta-analysis evaluates first-line treatment options for patients with EGFR-mutant non-small cell lung cancer (NSCLC) and brain metastases. We analyzed 24 randomized controlled trials (RCTs) involving 2,682 patients, comparing various EGFR tyrosine kinase...

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Tallennettuna:
Päätekijät: Jietao Ma, Xiaoxue Pang, Shuling Zhang, Letian Huang, Li Sun, Chengbo Han
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2024-10-01
Sarja:Scientific Reports
Aiheet:
EGFR-TKIs
Non-small cell lung cancer
Brain metastases
First-line therapy
Overall survival
Linkit:https://doi.org/10.1038/s41598-024-74496-0
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